New evidence suggests that AS01-based vaccines, beyond their established role in preventing shingles and respiratory syncytial virus (RSV), may also reduce the risk for dementia. The supportive data, published on June 25 in the journal NPJ Vaccines, underscores the importance of maintaining up-to-date immunizations, particularly among older adults. The study found that dementia risk dropped after AS01 vaccines. Patients who received the shingles (Shingrix) or RSV (Arexvy) vaccines- both containing the AS01 adjuvant- had a significantly lower risk for dementia over 18 months compared to those who received the flu vaccine. The study also found that there was an even greater protection when both vaccines were used.
Link: Medscape Medical News (07/2025)
