Incidence and Disease Burden of Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a common complication and is associated with long-term opioid use in cancer survivors. This retrospective population-based study evaluated the prevalence and long-term disease burden of CIPN among residents in Minnesota who were exposed to neurotoxic chemotherapy. Of the 509 individuals with incident exposure to neurotoxic chemotherapy, approximately half were determined to have CIPN. Pain symptoms and use of pain medications were observed more often in patients with CIPN. Individuals with CIPN surviving greater than 5 years (n=145) continued to have substantial impairments and were more likely to be prescribed opioids than those without CIPN.

 Link to: J Neurol Neurosurg Psychiatry (6/2018)