When patients with advanced cancer come to our palliative care clinic, they’re often struggling with symptoms like weight loss, and nausea and vomiting—especially when they are receiving treatment with a moderate- or high-risk emetogenic chemotherapy regimen. Most palliative care clinicians regularly prescribe typical first-line antiemetics like ondansetron and prochlorperazine for chemotherapy-induced nausea and vomiting (CINV). But now clinicians are increasingly turning to an atypical antipsychotic medication as an add-on treatment or even as a first-line antiemetic: olanzapine.
Link: Center to Advance Palliative Care (12/2025)